Jeremy J Berg
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Welcome!

I am an  Assistant Professor in the Department of Human Genetics at the University of Chicago. My work is broadly focused on the development of theoretical and statistical population genetic models to understand the impact of natural selection on patterns of genetic and phenotypic diversity.

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Recent Publications
2025
- Berg JJ, Li, X, Riall, K, Hayward, L, Sella, G. Mutation-selection-drift balance models of complex disease. Genetics. DOI: 10.1093/genetics/iyae211 [pdf]
- Blanc J, Berg JJ. Testing for differences in polygenic scores in the presence of confounding. Genetics. DOI: 10.1093/genetics/iyae211 [pdf]
- Shastry V, Berg JJ. Allele ages provide limited information about the strength of negative selection. Genetics. DOI: 10.1093/genetics/iyae211 [pdf]

2021
- Carlson MO, Rice DP, Berg JJ, Steinrücken M. Polygenic score accuracy in ancient samples: Quantifying the effects of allelic turnover. PLOS Genetics. DOI: 10.1371/journal.pgen.1010170 [pdf]

2019
- Fuller Z, Berg JJ, Mostafavi H, Sella G, Przeworski M. Measuring "Intolerance to Mutation" in Human Genetics Nature Genetics. DOI: 10.1038/s41588-019-0383-1 [pdf]
- Berg JJ*, Harpak A*, Sinnott-Armstrong N*, Jörgensen AM, Mostafavi H, Field Y, Boyle EA, Zhang X, Racimo F, Pritchard JK, Coop G. Reduced signal for polygenic adaptation of height in UK Biobank eLife. DOI: 10.7554/eLife.39725 [pdf]
- Josephs E, Berg JJ, Ross-Ibarra J, Coop G. Detecting adaptive differentiation in structured populations with genomic data and common gardens Genetics. DOI: 10.1534/genetics.118.301786 [pdf]
Recent Preprints
2025
- Blanc, J, Mawass, W Berg JJ.  Quantifying the susceptibility of polygenic scores to ancestry stratification.  bioRxiv. DOI: 10.64898/2025.12.04.692430 [pdf]
- Li, X, Berg JJ.  Background selection in recombining genomes and its consequences for the maintenance of variation in complex traits.  bioRxiv. DOI: 
10.1101/2025.05.27.656342 [pdf]
- Mawass, W, Matheson, J, Hernandez, U, Berg JJ, Masel, J.  Extinction vortices are drive more by a shortage of beneficial mutations than by deleterious mutation accumulation.  bioRxiv. DOI: 10.1101/2024.10.25.620329 [pdf]
- Smith, SP, Smith, OS, Mostafavi, H, Peng, D, Berg JJ, Edge, D, Harpak, A. A Litmus Test for Confounding in Polygenic Scores.  bioRxiv. DOI: 10.1101/2025.02.01.635985 [pdf]
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